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Synthetic biology advances for pharmaceutical production

Synthetic biology enables a new generation of microbial engineering for the biotechnological production of pharmaceuticals and other high-value chemicals. This review presents an overview of recent advances in the field, describing new computational and experimental tools for the discovery, optimiza...

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Detalles Bibliográficos
Autores principales: Breitling, Rainer, Takano, Eriko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4617476/
https://www.ncbi.nlm.nih.gov/pubmed/25744872
http://dx.doi.org/10.1016/j.copbio.2015.02.004
Descripción
Sumario:Synthetic biology enables a new generation of microbial engineering for the biotechnological production of pharmaceuticals and other high-value chemicals. This review presents an overview of recent advances in the field, describing new computational and experimental tools for the discovery, optimization and production of bioactive molecules, and outlining progress towards the application of these tools to pharmaceutical production systems.