Reappraisal of known malaria resistance loci in a large multi-centre study

Many human genetic associations with resistance to malaria have been reported but few have been reliably replicated. We collected data on 11,890 cases of severe malaria due to Plasmodium falciparum and 17,441 controls from 12 locations in Africa, Asia and Oceania. There was strong evidence of associ...

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Detalles Bibliográficos
Autores principales: Rockett, Kirk A., Clarke, Geraldine M., Fitzpatrick, Kathryn, Hubbart, Christina, Jeffreys, Anna E., Rowlands, Kate, Craik, Rachel, Jallow, Muminatou, Conway, David J., Bojang, Kalifa A., Pinder, Margaret, Usen, Stanley, Sisay-Joof, Fatoumatta, Sirugo, Giorgio, Toure, Ousmane, Thera, Mahamadou A., Konate, Salimata, Sissoko, Sibiry, Niangaly, Amadou, Poudiougou, Belco, Mangano, Valentina D., Bougouma, Edith C., Sirima, Sodiomon B., Modiano, David, Amenga-Etego, Lucas N., Ghansah, Anita, Koram, Kwadwo A., Wilson, Michael D., Enimil, Anthony, Evans, Jennifer, Amodu, Olukemi, Olaniyan, Subulade, Apinjoh, Tobias, Mugri, Regina, Ndi, Andre, Ndila, Carolyne M., Uyoga, Sophie, Macharia, Alexander, Peshu, Norbert, Williams, Thomas N., Manjurano, Alphaxard, Riley, Eleanor, Drakeley, Chris, Reyburn, Hugh, Nyirongo, Vysaul, Kachala, David, Molyneux, Malcolm, Dunstan, Sarah J., Phu, Nguyen Hoan, Ngoc Quyen, Nguyen Thi, Thai, Cao Quang, Hien, Tran Tinh, Manning, Laurens, Laman, Moses, Siba, Peter, Karunajeewa, Harin, Allen, Steve, Allen, Angela, Davis, Timothy M. E., Michon, Pascal, Mueller, Ivo, Green, Angie, Molloy, Sile, Johnson, Kimberly J., Kerasidou, Angeliki, Cornelius, Victoria, Hart, Lee, Vanderwal, Aaron, SanJoaquin, Miguel, Band, Gavin, Le, Si Quang, Pirinen, Matti, Sepúlveda, Nuno, Spencer, Chris C.A., Clark, Taane G., Agbenyega, Tsiri, Achidi, Eric, Doumbo, Ogobara, Farrar, Jeremy, Marsh, Kevin, Taylor, Terrie, Kwiatkowski, Dominic P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4617542/
https://www.ncbi.nlm.nih.gov/pubmed/25261933
http://dx.doi.org/10.1038/ng.3107

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