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Chromosomal Instability, Aneuploidy, and Gene Mutations in Human Sporadic Colorectal Adenomas

Whether in vivo specific gene mutations lead to chromosomal instability (CIN) and aneuploidy or viceversa is so far not proven. We hypothesized that aneuploidy among human sporadic colorectal adenomas and KRAS2 and APC mutations were not independent. Additionally, we investigated if 1p34–36 deletion...

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Detalles Bibliográficos
Autores principales: Giaretti, Walter, Molinu, Silvia, Ceccarelli, Jenny, Prevosto, Claudia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: IOS Press 2004
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4617587/
https://www.ncbi.nlm.nih.gov/pubmed/15623940
http://dx.doi.org/10.1155/2004/816591

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