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Various Statistical Methods in Use for Evaluating Human Malignant Gastric Specimens

This paper presents the use of certain statistical methods (comparison of means – independent samples t‐test, multiple linear regression analysis, multiple logistic regression analysis, analysis of clusters, etc.) included in the SPSS Statistical Package used to classify the patients quantitatively...

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Detalles Bibliográficos
Autores principales: Enchev, Ventzeslav, Vukov, Mircho
Formato: Online Artículo Texto
Lenguaje:English
Publicado: IOS Press 1998
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4617588/
https://www.ncbi.nlm.nih.gov/pubmed/9692683
http://dx.doi.org/10.1155/1998/149710
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author Enchev, Ventzeslav
Vukov, Mircho
author_facet Enchev, Ventzeslav
Vukov, Mircho
author_sort Enchev, Ventzeslav
collection PubMed
description This paper presents the use of certain statistical methods (comparison of means – independent samples t‐test, multiple linear regression analysis, multiple logistic regression analysis, analysis of clusters, etc.) included in the SPSS Statistical Package used to classify the patients quantitatively evaluated after a subtotal resection of their stomachs. The group consisted of 40 patients subdivided into two groups: primary neoplasia of the stomach (20 patients), and corresponding lymphogenic deposits in the abdominal perigastric lymph nodes (20 patients). Paraffin‐embedded tissue sections (thickness 4–5µm) prepared as consecutive hematoxylin‐eosin‐stained slides were morphometrically measured by a rotation of a graduated eyepiece‐micrometer; thus, we obtained the minor and major axes’ lengths of the elliptic nuclear profiles and the minor and major caliper diameters of the corresponding cellular profiles. These four variables were used to determine the dynamic changes in quantitative features of human gastric lesions when passing from normal histological structures, through hyperplastic processes (chronic gastritis), gastric precancer (ulcers and polyps with or without malignancy) till the development of primary carcinomas and their corresponding lymphogeneous metastases. Besides the increased cytomorphometrical measures, we also noted an opportunity to classify the patients according to these data as well as to add to the knowledge of our consultation system for clinical aid and use, recently published in the literature.
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spelling pubmed-46175882016-01-12 Various Statistical Methods in Use for Evaluating Human Malignant Gastric Specimens Enchev, Ventzeslav Vukov, Mircho Anal Cell Pathol Other This paper presents the use of certain statistical methods (comparison of means – independent samples t‐test, multiple linear regression analysis, multiple logistic regression analysis, analysis of clusters, etc.) included in the SPSS Statistical Package used to classify the patients quantitatively evaluated after a subtotal resection of their stomachs. The group consisted of 40 patients subdivided into two groups: primary neoplasia of the stomach (20 patients), and corresponding lymphogenic deposits in the abdominal perigastric lymph nodes (20 patients). Paraffin‐embedded tissue sections (thickness 4–5µm) prepared as consecutive hematoxylin‐eosin‐stained slides were morphometrically measured by a rotation of a graduated eyepiece‐micrometer; thus, we obtained the minor and major axes’ lengths of the elliptic nuclear profiles and the minor and major caliper diameters of the corresponding cellular profiles. These four variables were used to determine the dynamic changes in quantitative features of human gastric lesions when passing from normal histological structures, through hyperplastic processes (chronic gastritis), gastric precancer (ulcers and polyps with or without malignancy) till the development of primary carcinomas and their corresponding lymphogeneous metastases. Besides the increased cytomorphometrical measures, we also noted an opportunity to classify the patients according to these data as well as to add to the knowledge of our consultation system for clinical aid and use, recently published in the literature. IOS Press 1998 1998-01-01 /pmc/articles/PMC4617588/ /pubmed/9692683 http://dx.doi.org/10.1155/1998/149710 Text en Copyright © 1998 Hindawi Publishing Corporation.
spellingShingle Other
Enchev, Ventzeslav
Vukov, Mircho
Various Statistical Methods in Use for Evaluating Human Malignant Gastric Specimens
title Various Statistical Methods in Use for Evaluating Human Malignant Gastric Specimens
title_full Various Statistical Methods in Use for Evaluating Human Malignant Gastric Specimens
title_fullStr Various Statistical Methods in Use for Evaluating Human Malignant Gastric Specimens
title_full_unstemmed Various Statistical Methods in Use for Evaluating Human Malignant Gastric Specimens
title_short Various Statistical Methods in Use for Evaluating Human Malignant Gastric Specimens
title_sort various statistical methods in use for evaluating human malignant gastric specimens
topic Other
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4617588/
https://www.ncbi.nlm.nih.gov/pubmed/9692683
http://dx.doi.org/10.1155/1998/149710
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