A non-proteolytic role for ubiquitin in deadenylation of MHC-I mRNA by the RNA-binding E3-ligase MEX-3C

The regulation of protein and mRNA turnover is essential for many cellular processes. We recently showed that ubiquitin—traditionally linked to protein degradation—directly regulates the degradation of mRNAs through the action of a newly identified family of RNA-binding E3 ubiquitin ligases. How ubi...

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Detalles Bibliográficos
Autores principales: Cano, Florencia, Rapiteanu, Radu, Sebastiaan Winkler, G., Lehner, Paul J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Pub. Group 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4617606/
https://www.ncbi.nlm.nih.gov/pubmed/26471122
http://dx.doi.org/10.1038/ncomms9670

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4617606/
https://www.ncbi.nlm.nih.gov/pubmed/26471122
http://dx.doi.org/10.1038/ncomms9670

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