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Role of the cytoplasmic isoform of RBFOX1/A2BP1 in establishing the architecture of the developing cerebral cortex

BACKGROUND: RBFOX1 (also known as FOX1 or A2BP1) regulates alternative splicing of a variety of transcripts crucial for neuronal functions. Physiological significance of RBFOX1 during brain development is seemingly essential since abnormalities in the gene cause autism spectrum disorder (ASD) and ot...

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Detalles Bibliográficos
Autores principales: Hamada, Nanako, Ito, Hidenori, Iwamoto, Ikuko, Morishita, Rika, Tabata, Hidenori, Nagata, Koh-ichi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4617638/
https://www.ncbi.nlm.nih.gov/pubmed/26500751
http://dx.doi.org/10.1186/s13229-015-0049-5