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Fellow Eye Macular Edema Improvement after Intravitreal Bevacizumab for Radiation Retinopathy

Radiation retinopathy (RR) is a progressive, chronic condition directly related to the amount of radiation administered to the retina. We report a 37-year-old patient with medulloblastoma that was treated with external beam radiation and presented to us with bilateral cystoid macular edema. He was t...

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Autores principales: Brito, Isis A. S., Zacharias, Leandro C., Pimentel, Sérgio Luis G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4617700/
https://www.ncbi.nlm.nih.gov/pubmed/26635985
http://dx.doi.org/10.1155/2015/516921
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author Brito, Isis A. S.
Zacharias, Leandro C.
Pimentel, Sérgio Luis G.
author_facet Brito, Isis A. S.
Zacharias, Leandro C.
Pimentel, Sérgio Luis G.
author_sort Brito, Isis A. S.
collection PubMed
description Radiation retinopathy (RR) is a progressive, chronic condition directly related to the amount of radiation administered to the retina. We report a 37-year-old patient with medulloblastoma that was treated with external beam radiation and presented to us with bilateral cystoid macular edema. He was treated with monthly bevacizumab injections only in his worst seeing eye. There was a significant improvement in his fellow eye, with marked retinal thickness reduction. Therefore, we present clinical evidence of systemic absorption and fellow eye activity of the drug (bevacizumab). One must be aware of distant side effects after intravitreal injections.
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spelling pubmed-46177002015-12-03 Fellow Eye Macular Edema Improvement after Intravitreal Bevacizumab for Radiation Retinopathy Brito, Isis A. S. Zacharias, Leandro C. Pimentel, Sérgio Luis G. Case Rep Ophthalmol Med Case Report Radiation retinopathy (RR) is a progressive, chronic condition directly related to the amount of radiation administered to the retina. We report a 37-year-old patient with medulloblastoma that was treated with external beam radiation and presented to us with bilateral cystoid macular edema. He was treated with monthly bevacizumab injections only in his worst seeing eye. There was a significant improvement in his fellow eye, with marked retinal thickness reduction. Therefore, we present clinical evidence of systemic absorption and fellow eye activity of the drug (bevacizumab). One must be aware of distant side effects after intravitreal injections. Hindawi Publishing Corporation 2015 2015-10-08 /pmc/articles/PMC4617700/ /pubmed/26635985 http://dx.doi.org/10.1155/2015/516921 Text en Copyright © 2015 Isis A. S. Brito et al. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Brito, Isis A. S.
Zacharias, Leandro C.
Pimentel, Sérgio Luis G.
Fellow Eye Macular Edema Improvement after Intravitreal Bevacizumab for Radiation Retinopathy
title Fellow Eye Macular Edema Improvement after Intravitreal Bevacizumab for Radiation Retinopathy
title_full Fellow Eye Macular Edema Improvement after Intravitreal Bevacizumab for Radiation Retinopathy
title_fullStr Fellow Eye Macular Edema Improvement after Intravitreal Bevacizumab for Radiation Retinopathy
title_full_unstemmed Fellow Eye Macular Edema Improvement after Intravitreal Bevacizumab for Radiation Retinopathy
title_short Fellow Eye Macular Edema Improvement after Intravitreal Bevacizumab for Radiation Retinopathy
title_sort fellow eye macular edema improvement after intravitreal bevacizumab for radiation retinopathy
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4617700/
https://www.ncbi.nlm.nih.gov/pubmed/26635985
http://dx.doi.org/10.1155/2015/516921
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