Streptococcus pyogenes Sortase Mutants Are Highly Susceptible to Killing by Host Factors Due to Aberrant Envelope Physiology

Cell wall anchored virulence factors are critical for infection and colonization of the host by Gram-positive bacteria. Such proteins have an N-terminal leader sequence and a C-terminal sorting signal, composed of an LPXTG motif, a hydrophobic stretch, and a few positively charged amino acids. The s...

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Detalles Bibliográficos
Autores principales: Raz, Assaf, Tanasescu, Ana-Maria, Zhao, Anna M., Serrano, Anna, Alston, Tricia, Sol, Asaf, Bachrach, Gilad, Fischetti, Vincent A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4617865/
https://www.ncbi.nlm.nih.gov/pubmed/26484774
http://dx.doi.org/10.1371/journal.pone.0140784

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4617865/
https://www.ncbi.nlm.nih.gov/pubmed/26484774
http://dx.doi.org/10.1371/journal.pone.0140784

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