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Integrated metabolic modelling reveals cell-type specific epigenetic control points of the macrophage metabolic network
BACKGROUND: The reconstruction of context-specific metabolic models from easily and reliably measurable features such as transcriptomics data will be increasingly important in research and medicine. Current reconstruction methods suffer from high computational effort and arbitrary threshold setting....
Autores principales: | Pacheco, Maria Pires, John, Elisabeth, Kaoma, Tony, Heinäniemi, Merja, Nicot, Nathalie, Vallar, Laurent, Bueb, Jean-Luc, Sinkkonen, Lasse, Sauter, Thomas |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4617894/ https://www.ncbi.nlm.nih.gov/pubmed/26480823 http://dx.doi.org/10.1186/s12864-015-1984-4 |
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