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Integrated metabolic modelling reveals cell-type specific epigenetic control points of the macrophage metabolic network

BACKGROUND: The reconstruction of context-specific metabolic models from easily and reliably measurable features such as transcriptomics data will be increasingly important in research and medicine. Current reconstruction methods suffer from high computational effort and arbitrary threshold setting....

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Detalles Bibliográficos
Autores principales: Pacheco, Maria Pires, John, Elisabeth, Kaoma, Tony, Heinäniemi, Merja, Nicot, Nathalie, Vallar, Laurent, Bueb, Jean-Luc, Sinkkonen, Lasse, Sauter, Thomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4617894/
https://www.ncbi.nlm.nih.gov/pubmed/26480823
http://dx.doi.org/10.1186/s12864-015-1984-4

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