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Potential Link between the Sphingosine-1-Phosphate (S1P) System and Defective Alveolar Macrophage Phagocytic Function in Chronic Obstructive Pulmonary Disease (COPD)

INTRODUCTION: We previously reported that alveolar macrophages from patients with chronic obstructive pulmonary disease (COPD) are defective in their ability to phagocytose apoptotic cells, with a similar defect in response to cigarette smoke. The exact mechanisms for this defect are unknown. Sphing...

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Detalles Bibliográficos
Autores principales:	Barnawi, Jameel, Tran, Hai, Jersmann, Hubertus, Pitson, Stuart, Roscioli, Eugene, Hodge, Greg, Meech, Robyn, Haberberger, Rainer, Hodge, Sandra
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2015
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4617901/ https://www.ncbi.nlm.nih.gov/pubmed/26485657 http://dx.doi.org/10.1371/journal.pone.0122771

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