Exome sequencing of lymphomas from three dog breeds reveals somatic mutation patterns reflecting genetic background

Lymphoma is the most common hematological malignancy in developed countries. Outcome is strongly determined by molecular subtype, reflecting a need for new and improved treatment options. Dogs spontaneously develop lymphoma, and the predisposition of certain breeds indicates genetic risk factors. Us...

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Detalles Bibliográficos
Autores principales: Elvers, Ingegerd, Turner-Maier, Jason, Swofford, Ross, Koltookian, Michele, Johnson, Jeremy, Stewart, Chip, Zhang, Cheng-Zhong, Schumacher, Steven E., Beroukhim, Rameen, Rosenberg, Mara, Thomas, Rachael, Mauceli, Evan, Getz, Gad, Palma, Federica Di, Modiano, Jaime F., Breen, Matthew, Lindblad-Toh, Kerstin, Alföldi, Jessica
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2015
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4617960/
https://www.ncbi.nlm.nih.gov/pubmed/26377837
http://dx.doi.org/10.1101/gr.194449.115

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