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Structured nucleosome fingerprints enable high-resolution mapping of chromatin architecture within regulatory regions

Transcription factors canonically bind nucleosome-free DNA, making the positioning of nucleosomes within regulatory regions crucial to the regulation of gene expression. Using the assay of transposase accessible chromatin (ATAC-seq), we observe a highly structured pattern of DNA fragment lengths and...

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Detalles Bibliográficos
Autores principales:	Schep, Alicia N., Buenrostro, Jason D., Denny, Sarah K., Schwartz, Katja, Sherlock, Gavin, Greenleaf, William J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Cold Spring Harbor Laboratory Press 2015
Materias:	Method
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4617971/ https://www.ncbi.nlm.nih.gov/pubmed/26314830 http://dx.doi.org/10.1101/gr.192294.115

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