Independent Induction of Caspase-8 and cFLIP Expression during Colorectal Carcinogenesis in Sporadic and HNPCC Adenomas and Carcinomas

Background: TNF-Related Apoptosis Inducing Ligand (TRAIL) is a promising agent for the induction of apoptosis in neoplastic tissues. Important determinants of TRAIL sensitivity are two intracellular proteins of the TRAIL pathway, caspase-8 and its anti-apoptotic competitor cellular Flice-Like Inhibi...

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Detalles Bibliográficos
Autores principales: Heijink, D. M., Kleibeuker, J. H., Jalving, M., Boersma-van Ekb, W., Koornstra, J. J., Wesseling, J., de Jong, S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: IOS Press 2007
Materias:
Other
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4617989/
https://www.ncbi.nlm.nih.gov/pubmed/17726263
http://dx.doi.org/10.1155/2007/564605

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