The kinases Mst1 and Mst2 positively regulate phagocyte ROS induction and bactericidal activity

Mitochondria need to be juxtaposted to phagosomes to synergistically produce ample reactive oxygen species (ROS) in phagocytes for pathogens killing. However, how phagosomes transmit signal to recruit mitochondria remains unclear. Here, we report that the kinases Mst1 and Mst2 function to control RO...

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Detalles Bibliográficos
Autores principales: Geng, Jing, Sun, Xiufeng, Wang, Ping, Zhang, Shihao, Wang, Xiaozhen, Wu, Hongtan, Hong, Lixin, Xie, Changchuan, Li, Xun, Zhao, Hao, Liu, Qingxu, Jiang, Mingting, Chen, Qinghua, Zhang, Jinjia, Li, Yang, Song, Siyang, Wang, Hong-Rui, Zhou, Rongbin, Johnson, Randy L., Chien, Kun-Yi, Lin, Sheng-Cai, Han, Jiahuai, Avruch, Joseph, Chen, Lanfen, Zhou, Dawang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4618176/
https://www.ncbi.nlm.nih.gov/pubmed/26414765
http://dx.doi.org/10.1038/ni.3268

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