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Suppressors of superoxide production from mitochondrial complex III
Mitochondrial electron transport drives ATP synthesis but also generates reactive oxygen species (ROS), which are both cellular signals and damaging oxidants. Superoxide production by respiratory complex III is implicated in diverse signaling events and pathologies but its role remains controversial...
Autores principales: | Orr, Adam L., Vargas, Leonardo, Turk, Carolina N., Baaten, Janine E., Matzen, Jason T., Dardov, Victoria J., Attle, Stephen J., Li, Jing, Quackenbush, Douglas C., Goncalves, Renata L. S., Perevoshchikova, Irina V., Petrassi, H. Michael, Meeusen, Shelly L., Ainscow, Edward K., Brand, Martin D. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4618194/ https://www.ncbi.nlm.nih.gov/pubmed/26368590 http://dx.doi.org/10.1038/nchembio.1910 |
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