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Promoter Methylation Precedes Chromosomal Alterations in Colorectal Cancer Development

Background: Colorectal cancers are characterized by genetic and epigenetic alterations. This study aimed to explore the timing of promoter methylation and relationship with mutations and chromosomal alterations in colorectal carcinogenesis. Methods: In a series of 47 nonprogressed adenomas, 41 progr...

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Detalles Bibliográficos
Autores principales:	Derks, Sarah, Postma, Cindy, Moerkerk, Peter T. M., van den Bosch, Sandra M., Carvalho, Beatriz, Hermsen, Mario A. J. A., Giaretti, Walter, Herman, James G., Weijenberg, Matty P., de Bruïne, Adriaan P., Meijer, Gerrit A., van Engeland, Manon
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	IOS Press 2006
Materias:	Other
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4618222/ https://www.ncbi.nlm.nih.gov/pubmed/17167178 http://dx.doi.org/10.1155/2006/846251

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