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Chronic Arachidonic Acid Administration Decreases Docosahexaenoic Acid- and Eicosapentaenoic Acid-Derived Metabolites in Kidneys of Aged Rats
Arachidonic acid (ARA) metabolites produced by cyclo-oxygenase and lipoxygenase are important mediators maintaining physiological renal function. However, the effects of exogenous ARA on kidney function in vivo remain unknown. This study examined the effects of long-term oral ARA administration on n...
Autores principales: | Katakura, Masanori, Hashimoto, Michio, Inoue, Takayuki, Mamun, Abdullah Al, Tanabe, Yoko, Arita, Makoto, Shido, Osamu |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4618288/ https://www.ncbi.nlm.nih.gov/pubmed/26485038 http://dx.doi.org/10.1371/journal.pone.0140884 |
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