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Hypermethylation of the GATA binding protein 4 (GATA4) promoter in Chinese pediatric acute myeloid leukemia

BACKGROUND: Acute myeloid leukemia (AML) is the second-most common form of leukemia in children. Aberrant DNA methylation patterns are a characteristic feature of AML. GATA4 has been suggested to be a tumor suppressor gene regulated by promoter hypermethylation in various types of human cancers alth...

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Detalles Bibliográficos
Autores principales: Tao, Yan-Fang, Fang, Fang, Hu, Shao-Yan, Lu, Jun, Cao, Lan, Zhao, Wen-Li, Xiao, Pei-Fang, Li, Zhi-Heng, Wang, Na-Na, Xu, Li-Xiao, Du, Xiao-Juan, Sun, Li-Chao, Li, Yan-Hong, Li, Yi-Ping, Xu, Yun-Yun, Ni, Jian, Wang, Jian, Feng, Xing, Pan, Jian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4618362/
https://www.ncbi.nlm.nih.gov/pubmed/26490736
http://dx.doi.org/10.1186/s12885-015-1760-5

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