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EGFR and K-ras Mutation Analysis in Non-Small Cell Lung Cancer: Comparison of Paraffin Embedded versus Frozen Specimens

Background: Mutational analysis of the Epidermal Growth Factor Receptor (EGFR) and K-ras genes to select non-small cell lung cancer (NSCLC) patients for treatment with novel EGFR tyrosine kinase inhibitors is an appealing possibility currently under investigation. Although frozen tumor tissue would...

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Detalles Bibliográficos
Autores principales: Gallegos Ruiz, Mariëlle I., Floor, Karijn, Rijmen, Frank, Grünberg, Katrien, Rodriguez, José A, Giaccone, Giuseppe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: IOS Press 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4618423/
https://www.ncbi.nlm.nih.gov/pubmed/17452778
http://dx.doi.org/10.1155/2007/568205