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Conditional Inactivation of HIF-1 Using Intrabodies

Hypoxia is a hallmark of solid cancers and triggers the transcription of genes responsible for cell survival. The transcription factor Hypoxia-Inducible Factor 1 (HIF-1) is a key regulator in this response and frequently activated in human cancer. HIF-1 activation is associated with tumor aggressive...

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Detalles Bibliográficos
Autores principales:	Groot, Arjan J., Gort, Eelke H., van der Wall, Elsken, van Diest, Paul J., Vooijs, Marc
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	IOS Press 2008
Materias:	Other
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4618431/ https://www.ncbi.nlm.nih.gov/pubmed/18791271 http://dx.doi.org/10.3233/CLO-2008-0442

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