Tbx3 Controls Dppa3 Levels and Exit from Pluripotency toward Mesoderm

Tbx3, a member of the T-box family, plays important roles in development, stem cells, nuclear reprogramming, and cancer. Loss of Tbx3 induces differentiation in mouse embryonic stem cells (mESCs). However, we show that mESCs exist in an alternate stable pluripotent state in the absence of Tbx3. In-d...

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Detalles Bibliográficos
Autores principales: Waghray, Avinash, Saiz, Néstor, Jayaprakash, Anitha D., Freire, Ana G., Papatsenko, Dmitri, Pereira, Carlos-Filipe, Lee, Dung-Fang, Brosh, Ran, Chang, Betty, Darr, Henia, Gingold, Julian, Kelley, Kevin, Schaniel, Christoph, Hadjantonakis, Anna-Katerina, Lemischka, Ihor R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4618439/
https://www.ncbi.nlm.nih.gov/pubmed/26095607
http://dx.doi.org/10.1016/j.stemcr.2015.05.009

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