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Stereoselective synthesis of macrocyclic peptides via a dual olefin metathesis and ethenolysis approach
Macrocyclic compounds occupy an important chemical space between small molecules and biologics and are prevalent in many natural products and pharmaceuticals. The growing interest in macrocycles has been fueled, in part, by the design of novel synthetic methods to these compounds. One appealing stra...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Royal Society of Chemistry
2015
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4618480/ https://www.ncbi.nlm.nih.gov/pubmed/26509000 http://dx.doi.org/10.1039/c5sc01507c |