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Potential Biomarkers of Colorectal Adenoma–Dysplasia–Carcinoma Progression: mRNA Expression Profiling and In Situ Protein Detection on TMAs Reveal 15 Sequentially Upregulated and 2 Downregulated Genes
Background: As most colorectal cancers (CRC) develop from villous adenomas, studying alterations in gene expression profiles across the colorectal adenoma–dysplasia–carcinoma sequence may yield potential biomarkers of disease progression. Methods: Total RNA was extracted, amplified, and biotinylated...
Autores principales: | Galamb, Orsolya, Sipos, Ferenc, Spisák, Sándor, Galamb, Barnabás, Krenács, Tibor, Valcz, Gábor, Tulassay, Zsolt, Molnár, Béla |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
IOS Press
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4618585/ https://www.ncbi.nlm.nih.gov/pubmed/19096147 http://dx.doi.org/10.3233/CLO-2009-0458 |
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