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Klf2 and Tfcp2l1, Two Wnt/β-Catenin Targets, Act Synergistically to Induce and Maintain Naive Pluripotency

Activation of Wnt/β-catenin signaling can induce both self-renewal and differentiation in naive pluripotent embryonic stem cells (ESCs). To gain insights into the mechanism by which Wnt/β-catenin regulates ESC fate, we screened and characterized its downstream targets. Here, we show that the self-re...

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Detalles Bibliográficos
Autores principales:	Qiu, Dongbo, Ye, Shoudong, Ruiz, Bryan, Zhou, Xingliang, Liu, Dahai, Zhang, Qi, Ying, Qi-Long
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2015
Materias:	Report
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4618593/ https://www.ncbi.nlm.nih.gov/pubmed/26321140 http://dx.doi.org/10.1016/j.stemcr.2015.07.014

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