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Overexpression of the Mitotic Checkpoint Genes BUB1 and BUBR1 is Associated with Genomic Complexity in Clear Cell Kidney Carcinomas

Background: A defective mitotic checkpoint has been proposed to contribute to chromosomal instability (CIN). We have previously shown that expression changes of the mitotic arrest deficiency (MAD) gene family plays a role in renal cell cancer (RCC) characterized by numerical chromosomal changes, nam...

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Detalles Bibliográficos
Autores principales:	Pinto, Mafalda, Vieira, Joana, Ribeiro, Franclim R., Soares, Maria J., Henrique, Rui, Oliveira, Jorge, Jerónimo, Carmen, Teixeira, Manuel R.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	IOS Press 2008
Materias:	Other
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4618595/ https://www.ncbi.nlm.nih.gov/pubmed/18791270 http://dx.doi.org/10.3233/CLO-2008-0439

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