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Interleukin-25 Mediates Transcriptional Control of PD-L1 via STAT3 in Multipotent Human Mesenchymal Stromal Cells (hMSCs) to Suppress Th17 Responses

Multipotent human mesenchymal stromal cells (hMSCs) harbor immunomodulatory properties that are therapeutically relevant. One of the most clinically important populations of leukocytes is the interleukin-17A (IL-17A)-secreting T (Th17) lymphocytes. However, mechanisms of hMSC and Th17 cell interacti...

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Detalles Bibliográficos
Autores principales: Wang, Wei-Bei, Yen, Men-Luh, Liu, Ko-Jiunn, Hsu, Pei-Ju, Lin, Ming-Hong, Chen, Pei-Min, Sudhir, Putty-Reddy, Chen, Chein-Hung, Chen, Chung-Hsuan, Sytwu, Huei-Kang, Yen, B. Linju
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4618596/
https://www.ncbi.nlm.nih.gov/pubmed/26321145
http://dx.doi.org/10.1016/j.stemcr.2015.07.013