Cargando…
CEND1 and NEUROGENIN2 Reprogram Mouse Astrocytes and Embryonic Fibroblasts to Induced Neural Precursors and Differentiated Neurons
Recent studies demonstrate that astroglia from non-neurogenic brain regions can be reprogrammed into functional neurons through forced expression of neurogenic factors. Here we explored the effect of CEND1 and NEUROG2 on reprogramming of mouse cortical astrocytes and embryonic fibroblasts. Forced ex...
Autores principales: | Aravantinou-Fatorou, Katerina, Ortega, Felipe, Chroni-Tzartou, Dafni, Antoniou, Nasia, Poulopoulou, Cornelia, Politis, Panagiotis K., Berninger, Benedikt, Matsas, Rebecca, Thomaidou, Dimitra |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2015
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4618597/ https://www.ncbi.nlm.nih.gov/pubmed/26321141 http://dx.doi.org/10.1016/j.stemcr.2015.07.012 |
Ejemplares similares
-
A miR-124-mediated post-transcriptional mechanism controlling the cell fate switch of astrocytes to induced neurons
por: Papadimitriou, Elsa, et al.
Publicado: (2023) -
Increased Anxiety-Related Behavior, Impaired Cognitive Function and Cellular Alterations in the Brain of Cend1-deficient Mice
por: Segklia, Katerina, et al.
Publicado: (2019) -
Cend1, a Story with Many Tales: From Regulation of Cell Cycle Progression/Exit of Neural Stem Cells to Brain Structure and Function
por: Gaitanou, Maria, et al.
Publicado: (2019) -
Functional Interactions between BM88/Cend1, Ran-Binding Protein M and Dyrk1B Kinase Affect Cyclin D1 Levels and Cell Cycle Progression/Exit in Mouse Neuroblastoma Cells
por: Tsioras, Konstantinos, et al.
Publicado: (2013) -
Heterogeneity of neurons reprogrammed from spinal cord astrocytes by the proneural factors Ascl1 and Neurogenin2
por: Kempf, J., et al.
Publicado: (2021)