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Maackiain is a novel antiallergic compound that suppresses transcriptional upregulation of the histamine H(1) receptor and interleukin-4 genes
Kujin contains antiallergic compounds that inhibit upregulation of histamine H(1) receptor (H1R) and interleukin (IL)-4 gene expression. However, the underlying mechanism remains unknown. We sought to identify a Kujin-derived antiallergic compound and investigate its mechanism of action. The H1R and...
Autores principales: | Mizuguchi, Hiroyuki, Nariai, Yuki, Kato, Shuhei, Nakano, Tomohiro, Kanayama, Tomoyo, Kashiwada, Yoshiki, Nemoto, Hisao, Kawazoe, Kazuyoshi, Takaishi, Yoshihisa, Kitamura, Yoshiaki, Takeda, Noriaki, Fukui, Hiroyuki |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley & Sons, Ltd
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4618638/ https://www.ncbi.nlm.nih.gov/pubmed/26516579 http://dx.doi.org/10.1002/prp2.166 |
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