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FTY720 (Fingolimod) sensitizes hepatocellular carcinoma cells to sorafenib-mediated cytotoxicity

Hepatocellular carcinoma (HCC) is one of the leading causes of cancer-related death worldwide. The multityrosine kinase inhibitor sorafenib is used in the therapy of advanced disease. However, the effects of sorafenib are limited, and combination treatments aiming at improved survival are encouraged...

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Detalles Bibliográficos
Autores principales: Ahmed, Dilruba, de Verdier, Petra J, Ryk, Charlotta, Lunqe, Oscar, Stål, Per, Flygare, Jenny
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Ltd 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4618642/
https://www.ncbi.nlm.nih.gov/pubmed/26516583
http://dx.doi.org/10.1002/prp2.171