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C/EBPα Activates Pre-existing and De Novo Macrophage Enhancers during Induced Pre-B Cell Transdifferentiation and Myelopoiesis

Transcription-factor-induced somatic cell conversions are highly relevant for both basic and clinical research yet their mechanism is not fully understood and it is unclear whether they reflect normal differentiation processes. Here we show that during pre-B-cell-to-macrophage transdifferentiation,...

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Detalles Bibliográficos
Autores principales: van Oevelen, Chris, Collombet, Samuel, Vicent, Guillermo, Hoogenkamp, Maarten, Lepoivre, Cyrille, Badeaux, Aimee, Bussmann, Lars, Sardina, Jose Luis, Thieffry, Denis, Beato, Miguel, Shi, Yang, Bonifer, Constanze, Graf, Thomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4618662/
https://www.ncbi.nlm.nih.gov/pubmed/26235892
http://dx.doi.org/10.1016/j.stemcr.2015.06.007