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Activating Endogenous Neural Precursor Cells Using Metformin Leads to Neural Repair and Functional Recovery in a Model of Childhood Brain Injury

The development of cell replacement strategies to repair the injured brain has gained considerable attention, with a particular interest in mobilizing endogenous neural stem and progenitor cells (known as neural precursor cells [NPCs]) to promote brain repair. Recent work demonstrated metformin, a d...

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Detalles Bibliográficos
Autores principales: Dadwal, Parvati, Mahmud, Neemat, Sinai, Laleh, Azimi, Ashkan, Fatt, Michael, Wondisford, Fredric E., Miller, Freda D., Morshead, Cindi M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4618663/
https://www.ncbi.nlm.nih.gov/pubmed/26235894
http://dx.doi.org/10.1016/j.stemcr.2015.06.011

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