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Activating Endogenous Neural Precursor Cells Using Metformin Leads to Neural Repair and Functional Recovery in a Model of Childhood Brain Injury
The development of cell replacement strategies to repair the injured brain has gained considerable attention, with a particular interest in mobilizing endogenous neural stem and progenitor cells (known as neural precursor cells [NPCs]) to promote brain repair. Recent work demonstrated metformin, a d...
Autores principales: | Dadwal, Parvati, Mahmud, Neemat, Sinai, Laleh, Azimi, Ashkan, Fatt, Michael, Wondisford, Fredric E., Miller, Freda D., Morshead, Cindi M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4618663/ https://www.ncbi.nlm.nih.gov/pubmed/26235894 http://dx.doi.org/10.1016/j.stemcr.2015.06.011 |
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