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Perm-seq: Mapping Protein-DNA Interactions in Segmental Duplication and Highly Repetitive Regions of Genomes with Prior-Enhanced Read Mapping

Segmental duplications and other highly repetitive regions of genomes contribute significantly to cells’ regulatory programs. Advancements in next generation sequencing enabled genome-wide profiling of protein-DNA interactions by chromatin immunoprecipitation followed by high throughput sequencing (...

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Detalles Bibliográficos
Autores principales: Zeng, Xin, Li, Bo, Welch, Rene, Rojo, Constanza, Zheng, Ye, Dewey, Colin N., Keleş, Sündüz
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4618727/
https://www.ncbi.nlm.nih.gov/pubmed/26484757
http://dx.doi.org/10.1371/journal.pcbi.1004491

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