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Perm-seq: Mapping Protein-DNA Interactions in Segmental Duplication and Highly Repetitive Regions of Genomes with Prior-Enhanced Read Mapping
Segmental duplications and other highly repetitive regions of genomes contribute significantly to cells’ regulatory programs. Advancements in next generation sequencing enabled genome-wide profiling of protein-DNA interactions by chromatin immunoprecipitation followed by high throughput sequencing (...
Autores principales: | Zeng, Xin, Li, Bo, Welch, Rene, Rojo, Constanza, Zheng, Ye, Dewey, Colin N., Keleş, Sündüz |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4618727/ https://www.ncbi.nlm.nih.gov/pubmed/26484757 http://dx.doi.org/10.1371/journal.pcbi.1004491 |
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