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Reconstructing the Rasch-Built Myotonic Dystrophy Type 1 Activity and Participation Scale

INTRODUCTION: A previously published Rasch-built activity and participation scale specifically designed for patients with myotonic dystrophy type 1 (DM1) was criticized for having been constructed in a relatively small cohort of patients and containing items too broadly phrased for DM1 patients, thu...

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Detalles Bibliográficos
Autores principales: Hermans, Mieke C. E., Hoeijmakers, Janneke G. J., Faber, Catharina G., Merkies, Ingemar S. J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4618741/
https://www.ncbi.nlm.nih.gov/pubmed/26484877
http://dx.doi.org/10.1371/journal.pone.0139944
Descripción
Sumario:INTRODUCTION: A previously published Rasch-built activity and participation scale specifically designed for patients with myotonic dystrophy type 1 (DM1) was criticized for having been constructed in a relatively small cohort of patients and containing items too broadly phrased for DM1 patients, thus hampering its clinical use. METHODS: We report the results of the reconstructed Rasch-built DM1 activity and participation scale for clinical use (DM1-Activ(C)) through Rasch analyses using an expanded questionnaire containing 146 more simply phrased activity and participation inquiries completed by 340 patients with DM1. RESULTS: Through stepwise investigation including data quality control, model fit, response category ordering, local dependency and item bias, we succeeded in reconstructing the DM1-Activ(C) consisting of 25 items that showed good Rasch model fit, including construct convergent validity, items’ weights and persons’ locations reliability, and unidimensionality. CONCLUSION: The DM1-Activ(C) scale has been reconstructed and fulfills all modern clinimetric requirements. Its use is recommended in future longitudinal trials in patients with DM1 to determine its responsiveness.