Cargando…
Systems analysis of non-parenchymal cell modulation of liver repair across multiple regeneration modes
BACKGROUND: A hallmark of chronic liver disease is the impairment of the liver’s innate regenerative ability. In this work we use a computational approach to unravel the principles underlying control of liver repair following an acute physiological challenge. METHODS: We used a mathematical model of...
Autores principales: | Cook, Daniel, Ogunnaike, Babatunde A., Vadigepalli, Rajanikanth |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2015
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4618752/ https://www.ncbi.nlm.nih.gov/pubmed/26493454 http://dx.doi.org/10.1186/s12918-015-0220-9 |
Ejemplares similares
-
Cellular network modeling and single cell gene expression analysis reveals novel hepatic stellate cell phenotypes controlling liver regeneration dynamics
por: Cook, Daniel, et al.
Publicado: (2018) -
Elucidating the
Mechanisms of Dynamic and Robust Control
of the Liver Homeostatic Renewal Process: Cell Network Modeling and
Analysis
por: Cook, Daniel, et al.
Publicado: (2023) -
A Spatial Model of Hepatic Calcium Signaling and Glucose Metabolism Under Autonomic Control Reveals Functional Consequences of Varying Liver Innervation Patterns Across Species
por: Verma, Aalap, et al.
Publicado: (2021) -
Causality Analysis and Cell Network Modeling of Spatial Calcium Signaling Patterns in Liver Lobules
por: Verma, Aalap, et al.
Publicado: (2018) -
Robust dynamic balance of AP-1 transcription factors in a neuronal gene regulatory network
por: Miller, Gregory M, et al.
Publicado: (2010)