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Pangenome analysis of Bifidobacterium longum and site-directed mutagenesis through by-pass of restriction-modification systems

BACKGROUND: Bifidobacterial genome analysis has provided insights as to how these gut commensals adapt to and persist in the human GIT, while also revealing genetic diversity among members of a given bifidobacterial (sub)species. Bifidobacteria are notoriously recalcitrant to genetic modification, w...

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Detalles Bibliográficos
Autores principales:	O’Callaghan, A., Bottacini, F., O’Connell Motherway, M., van Sinderen, D.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2015
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4618763/ https://www.ncbi.nlm.nih.gov/pubmed/26489930 http://dx.doi.org/10.1186/s12864-015-1968-4

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