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HER-2/neu Amplification Testing in Breast Cancer by Multiplex Ligation-Dependent Probe Amplification in Comparison with Immunohistochemistry and In Situ Hybridization

Background: Assessment of HER-2/neu status in invasive breast cancer is crucial to establish eligibility for trastuzumab and taxane based chemotherapy. Next to immunohistochemistry (IHC) to evaluate protein overexpression, a second line gene amplification test is required for cases with equivocal pr...

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Detalles Bibliográficos
Autores principales:	Moelans, Cathy B., de Weger, Roel A., van Blokland, Marja T.M., Ezendam, Chantal, Elshof, Sabrina, Tilanus, Marcel G. J., van Diest, Paul J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	IOS Press 2009
Materias:	Other
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4618800/ https://www.ncbi.nlm.nih.gov/pubmed/19096145 http://dx.doi.org/10.3233/CLO-2009-0461

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