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A Quantitative Proteomic Analysis of Hemogenic Endothelium Reveals Differential Regulation of Hematopoiesis by SOX17

The in vitro derivation of hematopoietic stem cells (HSCs) from pluripotent stem cells (PSCs) is complicated by the existence of multiple overlapping embryonic blood cell programs called primitive, erythromyeloid progenitor (EMP), and definitive. As HSCs are only generated during the definitive stag...

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Detalles Bibliográficos
Autores principales: Clarke, Raedun L., Robitaille, Aaron M., Moon, Randall T., Keller, Gordon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4618836/
https://www.ncbi.nlm.nih.gov/pubmed/26267830
http://dx.doi.org/10.1016/j.stemcr.2015.07.008