Karyotype alteration generates the neoplastic phenotypes of SV40-infected human and rodent cells

BACKGROUND: Despite over 50 years of research, it remains unclear how the DNA tumor viruses SV40 and Polyoma cause cancers. Prevailing theories hold that virus-coded Tumor (T)-antigens cause cancer by inactivating cellular tumor suppressor genes. But these theories don’t explain four characteristics...

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Detalles Bibliográficos
Autores principales: Bloomfield, Mathew, Duesberg, Peter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4618876/
https://www.ncbi.nlm.nih.gov/pubmed/26500699
http://dx.doi.org/10.1186/s13039-015-0183-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4618876/
https://www.ncbi.nlm.nih.gov/pubmed/26500699
http://dx.doi.org/10.1186/s13039-015-0183-y

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