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Karyotype alteration generates the neoplastic phenotypes of SV40-infected human and rodent cells
BACKGROUND: Despite over 50 years of research, it remains unclear how the DNA tumor viruses SV40 and Polyoma cause cancers. Prevailing theories hold that virus-coded Tumor (T)-antigens cause cancer by inactivating cellular tumor suppressor genes. But these theories don’t explain four characteristics...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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BioMed Central
2015
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4618876/ https://www.ncbi.nlm.nih.gov/pubmed/26500699 http://dx.doi.org/10.1186/s13039-015-0183-y |