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Brucella infection of the thoracic vertebral arch presenting with an epidural abscess: a case report

INTRODUCTION: Although Brucella spondylitis and Brucella discitis have been frequently reported, Brucella infection of the vertebral arch is rare and has not been previously described. We present the first case of Brucella infection of the thoracic vertebral arch with epidural abscess formation and...

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Autores principales: Yin, ZhiXun, He, ErXing, Ding, HongMei, Chen, JingChen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4619028/
https://www.ncbi.nlm.nih.gov/pubmed/26496896
http://dx.doi.org/10.1186/s13256-015-0713-6
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author Yin, ZhiXun
He, ErXing
Ding, HongMei
Chen, JingChen
author_facet Yin, ZhiXun
He, ErXing
Ding, HongMei
Chen, JingChen
author_sort Yin, ZhiXun
collection PubMed
description INTRODUCTION: Although Brucella spondylitis and Brucella discitis have been frequently reported, Brucella infection of the vertebral arch is rare and has not been previously described. We present the first case of Brucella infection of the thoracic vertebral arch with epidural abscess formation and discuss the clinical key points. CASE PRESENTATION: A 57-year-old man of Han nationality with a history of contact with an isolated sheep stomach 2 months previously was admitted with an undulant fever, night sweats, back pain, and weakness. Thoracic magnetic resonance imaging showed laminar destruction of T9 and an epidural abscess at the T9 to 10 level with significant cord compression. Diagnosis of Brucella infection of his vertebral arch was confirmed by a positive blood culture with growth of Brucella melitensis. Total laminectomy, abscess cleansing, and percutaneous pedicular screw fixation was performed initially, followed by antibiotic treatment with a combination of doxycycline and rifampin for 4 months. Recovery was confirmed by clinical, magnetic resonance imaging, and blood culture findings. CONCLUSIONS: This is an unusual case of Brucella infection of the vertebral arch with epidural abscess formation. Effective antibiotic therapy of a sufficient duration and timely performance of surgical treatment are the key points in management of such cases.
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spelling pubmed-46190282015-10-25 Brucella infection of the thoracic vertebral arch presenting with an epidural abscess: a case report Yin, ZhiXun He, ErXing Ding, HongMei Chen, JingChen J Med Case Rep Case Report INTRODUCTION: Although Brucella spondylitis and Brucella discitis have been frequently reported, Brucella infection of the vertebral arch is rare and has not been previously described. We present the first case of Brucella infection of the thoracic vertebral arch with epidural abscess formation and discuss the clinical key points. CASE PRESENTATION: A 57-year-old man of Han nationality with a history of contact with an isolated sheep stomach 2 months previously was admitted with an undulant fever, night sweats, back pain, and weakness. Thoracic magnetic resonance imaging showed laminar destruction of T9 and an epidural abscess at the T9 to 10 level with significant cord compression. Diagnosis of Brucella infection of his vertebral arch was confirmed by a positive blood culture with growth of Brucella melitensis. Total laminectomy, abscess cleansing, and percutaneous pedicular screw fixation was performed initially, followed by antibiotic treatment with a combination of doxycycline and rifampin for 4 months. Recovery was confirmed by clinical, magnetic resonance imaging, and blood culture findings. CONCLUSIONS: This is an unusual case of Brucella infection of the vertebral arch with epidural abscess formation. Effective antibiotic therapy of a sufficient duration and timely performance of surgical treatment are the key points in management of such cases. BioMed Central 2015-10-23 /pmc/articles/PMC4619028/ /pubmed/26496896 http://dx.doi.org/10.1186/s13256-015-0713-6 Text en © Yin et al. 2015 Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.
spellingShingle Case Report
Yin, ZhiXun
He, ErXing
Ding, HongMei
Chen, JingChen
Brucella infection of the thoracic vertebral arch presenting with an epidural abscess: a case report
title Brucella infection of the thoracic vertebral arch presenting with an epidural abscess: a case report
title_full Brucella infection of the thoracic vertebral arch presenting with an epidural abscess: a case report
title_fullStr Brucella infection of the thoracic vertebral arch presenting with an epidural abscess: a case report
title_full_unstemmed Brucella infection of the thoracic vertebral arch presenting with an epidural abscess: a case report
title_short Brucella infection of the thoracic vertebral arch presenting with an epidural abscess: a case report
title_sort brucella infection of the thoracic vertebral arch presenting with an epidural abscess: a case report
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4619028/
https://www.ncbi.nlm.nih.gov/pubmed/26496896
http://dx.doi.org/10.1186/s13256-015-0713-6
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