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Sequence conservation analysis and in silico human leukocyte antigen-peptide binding predictions for the Mtb72F and M72 tuberculosis candidate vaccine antigens

BACKGROUND: Requisites for an efficacious tuberculosis (TB) vaccine are a minimal genomic diversity among infectious Mycobacterium tuberculosis strains for the selected antigen, and the capability to induce robust T-cell responses in the majority of human populations. A tool in the identification of...

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Detalles Bibliográficos
Autores principales: Mortier, Marie-Cécile, Jongert, Erik, Mettens, Pascal, Ruelle, Jean-Louis
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4619029/
https://www.ncbi.nlm.nih.gov/pubmed/26493839
http://dx.doi.org/10.1186/s12865-015-0119-7