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Sequence conservation analysis and in silico human leukocyte antigen-peptide binding predictions for the Mtb72F and M72 tuberculosis candidate vaccine antigens
BACKGROUND: Requisites for an efficacious tuberculosis (TB) vaccine are a minimal genomic diversity among infectious Mycobacterium tuberculosis strains for the selected antigen, and the capability to induce robust T-cell responses in the majority of human populations. A tool in the identification of...
Autores principales: | Mortier, Marie-Cécile, Jongert, Erik, Mettens, Pascal, Ruelle, Jean-Louis |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4619029/ https://www.ncbi.nlm.nih.gov/pubmed/26493839 http://dx.doi.org/10.1186/s12865-015-0119-7 |
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