Different Angiogenic Potential in Low and High Grade Sporadic Clear Cell Renal Cell Carcinoma Is Not Related to Alterations in the von Hippel–Lindau Gene

Background: von Hippel–Lindau (VHL) inactivation is common in sporadic clear cell renal cell carcinomas (ccRCC). pVHL is part of the ubiquitin ligase complex that targets the alpha subunits of hypoxia-inducible transcription factor (HIF) for degradation under well-oxygenated conditions. In the absen...

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Detalles Bibliográficos
Autores principales: Baldewijns, Marcella M., van Vlodrop, Iris J. H., Smits, Kim M., Vermeulen, Peter B., Van den Eynden, Gert G., Schot, Fiona, Roskams, Tania, van Poppel, Hein, van Engeland, Manon, de Bruïne, Adriaan P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: IOS Press 2009
Materias:
Other
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4619045/
https://www.ncbi.nlm.nih.gov/pubmed/19759417
http://dx.doi.org/10.3233/CLO-2009-0482

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