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Fas-Induced Apoptosis of Renal Cell Carcinoma is Mediated by Apoptosis Signal-Regulating Kinase 1 via Mitochondrial Damage-Dependent Caspase-8 Activation

Renal cell carcinoma (RCC) is a prototype of a chemo refractory tumour. It remains the most lethal of the common urologic cancers and is highly resistant to conventional therapy. Here, we confirmed the efficiency of anti-Fas monoclonal antibody (CH11) as alternative therapeutic approach for the trea...

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Detalles Bibliográficos
Autores principales:	Hassan, Mohamed, Feyen, Oliver, Grinstein, Edgar
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	IOS Press 2009
Materias:	Other
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4619051/ https://www.ncbi.nlm.nih.gov/pubmed/19940360 http://dx.doi.org/10.3233/CLO-2009-0488

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