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Phylogenomics and sequence-structure-function relationships in the GmrSD family of Type IV restriction enzymes
BACKGROUND: GmrSD is a modification-dependent restriction endonuclease that specifically targets and cleaves glucosylated hydroxymethylcytosine (glc-HMC) modified DNA. It is encoded either as two separate single-domain GmrS and GmrD proteins or as a single protein carrying both domains. Previous stu...
Autores principales: | Machnicka, Magdalena A., Kaminska, Katarzyna H., Dunin-Horkawicz, Stanislaw, Bujnicki, Janusz M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4619093/ https://www.ncbi.nlm.nih.gov/pubmed/26493560 http://dx.doi.org/10.1186/s12859-015-0773-z |
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