Methotrexate polyglutamates as a potential marker of adherence to long-term therapy in children with juvenile idiopathic arthritis and juvenile dermatomyositis: an observational, cross-sectional study

INTRODUCTION: Methotrexate (MTX) is a cornerstone of treatment in a wide variety of inflammatory conditions, including juvenile idiopathic arthritis (JIA) and juvenile dermatomyositis (JDM). However, owing to its narrow therapeutic index and the considerable interpatient variability in clinical resp...

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Detalles Bibliográficos
Autores principales: Hawwa, Ahmed F., AlBawab, AbdelQader, Rooney, Madeleine, Wedderburn, Lucy R., Beresford, Michael W., McElnay, James C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4619187/
https://www.ncbi.nlm.nih.gov/pubmed/26493320
http://dx.doi.org/10.1186/s13075-015-0814-z

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