Soluble CD40 Ligand in Sera of Subjects Exposed to Leishmania infantum Infection Reduces the Parasite Load in Macrophages

BACKGROUND: While CD40L is typically a membrane glycoprotein expressed on activated T cells and platelets that binds and activates CD40 on the surface on antigen presenting cells, a soluble derivative (sCD40L) that appears to retain its biological activity after cleavage from cell membrane also exis...

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Detalles Bibliográficos
Autores principales: de Oliveira, Fabrícia Alvisi, Barreto, Aline Silva, Bomfim, Lays G. S., Leite, Talita Rebeca S., dos Santos, Priscila Lima, de Almeida, Roque Pacheco, da Silva, Ângela Maria, Duthie, Malcolm S., Reed, Steven G., de Moura, Tatiana Rodrigues, Ribeiro de Jesus, Amélia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4619201/
https://www.ncbi.nlm.nih.gov/pubmed/26488744
http://dx.doi.org/10.1371/journal.pone.0141265

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