Mechanical Loading Synergistically Increases Trabecular Bone Volume and Improves Mechanical Properties in the Mouse when BMP Signaling Is Specifically Ablated in Osteoblasts

Bone homeostasis is affected by several factors, particularly mechanical loading and growth factor signaling pathways. There is overwhelming evidence to validate the importance of these signaling pathways, however, whether these signals work synergistically or independently to contribute to proper b...

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Detalles Bibliográficos
Autores principales: Iura, Ayaka, McNerny, Erin Gatenby, Zhang, Yanshuai, Kamiya, Nobuhiro, Tantillo, Margaret, Lynch, Michelle, Kohn, David H., Mishina, Yuji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4619208/
https://www.ncbi.nlm.nih.gov/pubmed/26489086
http://dx.doi.org/10.1371/journal.pone.0141345

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