WNT-Pathway Activation in IBD-Associated Colorectal Carcinogenesis: Potential Biomarkers for Colonic Surveillance

Objectives: The Wnt-pathway dominates the sporadic carcinogenesis whereas p53 plays a pivotal role in the colitis-associated counterpart. The expression of Wnt-signaling proteins and p53 during colitis-associated carcinogenesis was determined. Methods: A tissue microarray was constructed with coloni...

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Detalles Bibliográficos
Autores principales: Claessen, Marian M. H., Schipper, Marguerite E. I., Oldenburg, Bas, Siersema, Peter D., Offerhaus, G. Johan A., Vleggaar, Frank P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: IOS Press 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4619233/
https://www.ncbi.nlm.nih.gov/pubmed/20208143
http://dx.doi.org/10.3233/CLO-2009-0503

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