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Path Similarity Analysis: A Method for Quantifying Macromolecular Pathways

Diverse classes of proteins function through large-scale conformational changes and various sophisticated computational algorithms have been proposed to enhance sampling of these macromolecular transition paths. Because such paths are curves in a high-dimensional space, it has been difficult to quan...

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Detalles Bibliográficos
Autores principales: Seyler, Sean L., Kumar, Avishek, Thorpe, M. F., Beckstein, Oliver
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4619321/
https://www.ncbi.nlm.nih.gov/pubmed/26488417
http://dx.doi.org/10.1371/journal.pcbi.1004568